Gene description for TRIM21
Gene name tripartite motif containing 21
Gene symbol TRIM21
Other names/aliases RNF81
RO52
Ro/SSA
SSA
SSA1
Species Homo sapiens
 Experiment description of studies that identified TRIM21 in Pancreatic cancer cells

1
Experiment ID3346
Identified moleculeprotein
Extracellular vesicle typeSupermeres
MISEVEV-like nanoparticles
Identification method Mass spectrometry
PubMed ID 34887515   
OrganismHomo sapiens
Experiment descriptionSupermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
AuthorsZhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ.
Journal name Nat Cell Biol
Publication year2021
SamplePancreatic cancer cells
Sample namePANC-1
Isolation/purification methodsDifferential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWestern blotting
Mass spectrometry
ELISA
EV-TRACK -

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